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DESCRIPTION:

Sandosphere LAR® is long-acting release somatostatin analogue. Sandosphere LAR® is supplied in a sterile lyophilized form as a white to white-off powder in vials containing 20 mg of octreotide acetate and accompanied by solvent ampule containing 2.5 ml of mannitol and sodium-carboxymethyl cellulose, syringe and two needles (Long and short).

Sandosphere LAR® API is manufactured in Bachem Co. Switzerland and Corbion Co. Netherland, microsphere developed by Primm Co, Italy and developed by Homa pharmed Co.

Indication:

Special Warning and precautions:

GH reduction ang IGF1 balancing may cause restoring fertility power. So, Women of reproductive age are advised to use appropriate contraceptives during treatment with Octreotide if they do not intend to get pregnant.

Administration

Sandosphere LAR® should be administered by a trained healthcare provider. It is essential to follow the mixing instructions including in the packaging, closely.

Sandosphere LAR® must be administered immediately after mixing.

Sandosphere LAR® should be administrated intramuscularly in the gluteal region at 4-week intervals and administration intervals should not be more than 4 weeks.

Injection sites should be rotated systematically to avoid irritation.

Deltoid injection should be avoided due to significant discomfort at the injection site.

Use Long needle for preparing suspension and short needle for injection.

Do not warm it artificially

Side effects:

Prevalent:

Diarrhea, Fatigue, Nausea, Vomiting, Headache, Abdominal pain, Constipation, Flatulence, Thyroid disfunction, Gall bladder abnormalities, Hyperbilirubinemia, Impaired glucose tolerance, Blood glucose disturbances, Vit B deficiency

Contraindication:

Hypersensitivity to Octreotide Acetate or any component of to this drug

Storage:

Sandosphere LAR® should be stored at refrigerated temperature 2-8 ˚C and protect from light.

Sandosphere LAR® should be allowed to come to room temperature 30 minutes before preparing but do not to exceed 24 hours.

Keep away from children.

It is our honor to help patients who are suffering from the disease. We always hope to have a greater share in resolving diseases in the hope of getting rid of any suffering.

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