MICRORELIN ® is a Synthetic agonist of GNRH which possesses greater potency than the natural hormone. Gonadotrophin Releasing Hormone (GnRh) released from Hypothalamus responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary.
MICRORELIN ® has a sustained release formulation which allows continuous release of drug over 28 days. Naturally, GnRh Secretion is Pulsatile to Stimulate the secretion of Sex hormones. When it is given continuously in therapeutic doses, there is an initial and transient increase in circulating levels of LH, FSH and Testosterone. Continues administration of MICRORELIN ® result in an inhibition of pituitary Sex Hormones by 95%.
MICRORELIN ® API is manufactured in Bachem Co. Switzerland and Corbion Co. Netherland, microsphere developed by Primm Co, Italy and developed by Homa pharmed Co.
MICRORELIN ® is provided as lyophilized powder in 5 ml glass containing 3.75 Triptorelin acetate within microparticles and additives. Plus, an ampule containing 2 ml of vehicle for reconstitution of powder for IM Injection.