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DESCRIPTION:

MICRORELIN ® is a Synthetic agonist of GNRH which possesses greater potency than the natural hormone. Gonadotrophin Releasing Hormone (GnRh) released from Hypothalamus responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary.

MICRORELIN ® has a sustained release formulation which allows continuous release of drug over 28 days. Naturally, GnRh Secretion is Pulsatile to Stimulate the secretion of Sex hormones. When it is given continuously in therapeutic doses, there is an initial and transient increase in circulating levels of LH, FSH and Testosterone. Continues administration of MICRORELIN ® result in an inhibition of pituitary Sex Hormones by 95%.

MICRORELIN ® API is manufactured in Bachem Co. Switzerland and Corbion Co. Netherland, microsphere developed by Primm Co, Italy and developed by Homa pharmed Co.

MICRORELIN ® is provided as lyophilized powder in 5 ml glass containing 3.75 Triptorelin acetate within microparticles and additives. Plus, an ampule containing 2 ml of vehicle for reconstitution of powder for IM Injection.

Special warning & Precautions:

Indication:

Side effects:

The most commonly observed adverse events during triptorelin treatment are due to the expected physiological effects related to decreased testosterone levels. These effects included hot flushes, erectile dysfunction, and decreased libido. Other side effects are weakness and/or paresthesia of the lower limbs, allergic reaction, nausea, vomiting, weight gain, hypertension, mood disorders, visual disturbances, fever or pain at the injection site may occur.

Administration

MICRORELIN ® should be administered by a trained healthcare provider. It is essential to follow the mixing instructions including in the packaging, closely.

MICRORELIN ® should be administrated intramuscularly in the gluteal region at 4-week intervals and administration intervals should not be more than 4 weeks.

Storage

MICRORELIN ® should be stored between 15-25°C.

Keep away from children.

It is our honor to help patients who are suffering from the disease. We always hope to have a greater share in resolving diseases in the hope of getting rid of any suffering.

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