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DESCRIPTION:

Karma-HMG® is a hormonal substance containing FSH and LH in a ratio of 1:1.

In women karma-HMG® stimulates both the growth and the maturation of follicles, it induces an increase in the estrogen levels and a proliferation of the endometrium. In men, karma-HMG® stimulates spermatogenesis by acting on the production of the androgen-binding protein in the seminiferous tubules of the Sertoli cells

Karma-HMG® packed as three vials with lyophilized powder and accompanied by three ampoules of 1ml Sodium Chloride injection B.P. as solvent.

Karma-HMG® is manufactured in BSV Co. (Bioscience Gmbh) and is developed by Homa Pharmed Co. under license of Karma Pharmatech, Germany

Indication:

Administration

Karma-HMG® is given by intramuscular or subcutaneous injection. The powder for injection should be reconstituted with the Sodium Chloride Injection immediately prior to use. Discard any unused portion.

CONTRA-INDICATION AND WARNINGS:

Women

karma-HMG® therapy is precluded when an effective response cannot be obtained e.g. Ovarian dysgenesis, Absence of uterus, Premature menopause, Tubular occlusion.

Men

Patients with elevated endogenous FSH levels indicative of primary testicular failure are usually unresponsive to karma-HMG® and karma-HCG® (Chorionic Gonadotrophin Injection) therapy. Appropriate treatment should first be given for hypothyroidism, adrenocortical deficiency, hyperprolactinaemia or pituitary tumour. An acceptable semen analysis should be available before karma-HMG® treatment.

Side effects:

Injection site reactions, fever, arthralgia, gynecomastia.

Storage:

Karma-HMG® should be stored between °2C–°8C and protected from light. Do not freeze. Solution of Karma-FSH® reconstituted in Sodium Chloride Injection should be used immediately after preparation. Discard any unused portion. Keep away from children

It is our honor to help patients who are suffering from the disease. We always hope to have a greater share in resolving diseases in the hope of getting rid of any suffering.

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